Vegas is my least favorite place to club -- I only do it with my buddies, as basically a "wooo! Vegas!" male bonding thing. Set your expectations very low, and maybe you'll be pleasantly surprised. The hustle level at places like SR and Sapphire are insane. Even the club is hustling to an insane extent -- if you go to the ATM, expect 15% (not $15 -- 15%) surcharge on whatever you withdraw. This basically sets the tone for the entire experience, the ATM machine is going to rape you and it's the least shark-ish in the club.
That said, if money is TRULY no object, you can get OTC with an incredibly beautiful stripper for $1000 for sure. But just beware, there's a high percentage chance she's trying to hustle or otherwise rip you off -- be smart about when you pay her.
As with everywhere else, day shift will be way more mellow, with lower quality shifts, but lower hustle, lower-priced OTC available, etc.
Palomino is probably my fave club. Nudity + alcohol is a unique experience for me, and is downright intoxicating. Love it.
Spearmint Rhino and Sapphire have the hottest girls -- it is mind-numbing how hot -- but the most hustle. I haven't been to CH3 for a while, but when I last went, it was more to my taste -- a bit lower quality but concurrent lower hustle too. A good compromise if you're set on going to a club like this.