Why Don’t More Americans Use PrEP?
Rb47
Not on drugs
"Truvada, the brand name for a type of pre-exposure prophylaxis, or PrEP, is up to 99 percent effective at preventing H.I.V. infection."
Anyone have experience with PrEP or know anything or have an opinion about it?
Got something to say?
Start your own discussion
29 comments
Latest
I think the costs may be high.
Do other people have info about this?
SJG
https://www.sccgov.org/sites/phd/service…
https://www.avert.org/living-with-hiv/an…
Here, this is March 7th
https://www.mercurynews.com/2019/03/07/s…
https://www.sccgov.org/sites/phd/news/Pa…
http://gettingtozeroscc.org/
I don't think they are pitching it at those not in high risk groups, and the costs then might not be covered. I really don't know though.
SJG
Curious to know more about it.
SJG
For the same reason they don't walk around wearing a parachute.
It seems like a very-good med on the surface; but as has been noted, there are potentially undesirable side-effects - not sure how common/severe these side-effects are; pretty-much most medicines have some concerning possible side-effects but IDK how much of that is having to specify the fine-print and how much is that it being fairly-common side-effects - but w.r.t. PrEP it does seem the side-effects are of genuine concern - a few weeks ago I was watching on C-SPAN some pharmaceutical exec getting grilled in front of Congress about drug-costs; PrEP was one of the drugs discussed and one of the things the pharma exec said is that they are currently working on next generation PrEP-type drugs that have less side-effects - the little I know is that PrEP is recommended to be taken for a period of time where one may be engaged in risky-sex but supposedly not recommended to be taken continuously I assume b/c of the side-effects - I think participating on a message-board w/ folks that are taking this (perhaps a gay website); one would get some hands-on advice.
As has been mentioned; it's expensive - but from what I've heard if one pursues it w/ their insurance company they may often approve it on the thought that using PrEP as a preventative med is cheaper than treating a person that becomes HIV+ - also; one can often get brand-name meds a lot cheaper thru Canadian pharmacies; although for PrEP is would still be pretty-expensive.
Right now it's mostly marketed to, and used by, gay and bisexual men. This makes sense given that they are the high risk group. Most people with little chance of getting HIV are unlikely to find the expense to be worth it.
And then there is a different version of it for those already HIV positive. I don't know what is actually different about it, or why.
SJG
Heterosexuals can still qualify ( if they have unprotected with high risk partners. High risk partners defined as iv drug users or MSM)
The CDC has a nice info page
For those already HIV positive there is some other version of the medication.
So something does not sound right about that testing every 3 months.
SJG
So with that said, a white hetero male taking a very expensive drug with potentially powerful side effects, just to avoid something he doesn't have a realistic chance of catching unless he suddenly decide to take it up the ass from a lady boy or stick a needle in his arm, doesn't make a lot of sense.
So yes, I think this does raise many questions.
SJG
HIV is actually pretty hard to spread during regular heterosexual intercourse.
Indicated for those who do not currently have HIV, but engage in high risk activities that may contract HIV. An initial history of last 6 months activity.
Condomless penile-anal or penile-vaginal sex with someone other that their regular partner. ... ATF / CF Doesn’t count as regular for this scenario
The HIV serostatus of the partner
If sex is being had while using drugs
If you have had any other sexually transmitted infections
Number of sex partners
Serologic testing for syphilis
Nucleic acid amplification test for gonorrhea and chlamydia at mucosal sites
Drug use behavior : injecting heroin or cocaine, sharing needles/equipment, using non IV drugs like methamphetamine during sex (less likely to use condoms when stoned or high).
Get plasma HIV test prior to starting therapy. Use of 4 th Generation antigen/antibody assay preferred.
Kidney function tests to show kidneys at greater than 60 ml/min creatinine clearance. You old bastards will probably not qualify on this alone.
If you have diabetes, hypertension, greater than 40 years old, or renal toxic drugs like ibuprofen, then urinalysis to assess for proteinuria and glucosuria.
Hepatitis B and C screening
Osteoporosis screening
When you finally decide to take this therapy, you will be screened/tested every 3 months.
When you start the therapy, you need to wait 7 days for males and 21 days for females. One exception is that if you only like taking it up the ass, then you can take it more as needed if desired (concentration of drug in the anal tissue is high and achievable rapidly ).
You absolutely need to take it DAILY Without missing doses to give you that 90 percent or better protection rate.
Main adverse effects are
Osteoporosis long term
Bone fracture 2 %
Kidney failure
Liver enlargement
Lactic acidosis
Immune reconstitution syndrome
Headache 7%
Weight loss 3%
Abdominal pain 4%
There you have it. You you can now make a more educated decision as to whether or not to try this out. YMMV.
Why don't strippers count?
Got links for the above material?
SJG
As far as “links”. Yes, but if I shared them, I would have to charge you my $250 / hr fee. It is what I do. Take it or leave it.