I have a dancer friend who is 34 and burned out from the drinking and the life. Because of the cash flow she's been reluctant to quit, and because she works at something that burned her out, she compensates by drinking way through the day to make the bad time a good one. Didn't work for her . Won't work for most anyone else either. She's now working a more normal job. Sos leonard3, the answer is--it varies, but it will come during the 30-something decade for most. In my observation, it boils down to a state of mind issue.
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I am suprised by how long a functioning alcoholic can keep going, but a 30 Year old dancer has the clock running down on her anyway...
My guess is that 2 years will show some physical symptoms.
My guess is that 5 years will show some mental impairment as well.
If you have the gene for alcohol abuse, you find a way to stop or greatly reduce - or you die early...